| 张文涛1, 张斌斌2, 徐 军2, 吴小虎2, 董丰收2, 郑永权2, 王国宾1, 3*, 潘兴鲁2*.基于微流控芯片的农药残留检测研究进展[J].植物保护,2025,51(3):74-84. |
| 基于微流控芯片的农药残留检测研究进展 |
| Research progress on pesticide residue detection based on microfluidic chips |
| 投稿时间：2024-06-03 修订日期：2024-08-12 |
| DOI：10.16688/j.zwbh.2024303 |
| 中文关键词: 农药残留 微流控芯片 快速检测 微型化与集成化 |
| 英文关键词:pesticide residues microfluidic chips rapid detection miniaturization and integration |
| 基金项目:国家自然科学基金 (32272601) |
| 作者 | 单位 | E-mail | | 张文涛1, 张斌斌2, 徐 军2, 吴小虎2, 董丰收2, 郑永权2, 王国宾1, 3*, 潘兴鲁2* | 1. 山东理工大学农业工程与食品科学学院, 淄博 255049
2. 中国农业科学院植物保护研究所, 植物病虫害综合治理全国重点实验室, 北京 100193
3. 山东省农业航空智能装备工程技术研究中心, 淄博 255049 | 王国宾guobinwang@sdut.edu.cn;潘兴鲁panxinglu@caas.cn |
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| 中文摘要: |
| 化学农药在农作物病虫草害防治及其生长调节中发挥了重要作用, 然而农药的不合理施用导致的农产品农药残留问题不容忽视。因此, 建立快速精确的农药残留检测方法对推进农产品质量监管标准的制定, 提升公众健康水平和改善生态环境均具有重要意义。传统的仪器检测方法灵敏度与准确度高, 但因其专业性要求较高且难以实现微型化与集成化而不能满足现场实时快速检测的需求, 而微流控芯片凭借其小型化、低样品消耗以及易于集成等固有优势得到了快速发展。随着农药残留快速检测需求的不断提升以及微流控芯片制备材料和工艺的不断创新, 研发快速、高灵敏度的农药残留检测技术是现阶段微流控芯片在农药残留检测领域的主流发展方向。本文综述了应用于农药残留检测领域的微流控芯片的材料、制作工艺以及常用的流体驱动方式, 并详细介绍了微流控芯片在农药残留快速检测方面的研究进展, 对目前该技术在农药残留检测方面存在的一些问题作了简要总结并提出了可能的解决方案, 以期为农药残留快速检测新方法、新技术、新产品的研发提供参考。 |
| 英文摘要: |
| Chemical pesticides play an important role in controlling crop diseases, insects and weeds, as well as in regulating their growth. However, the irrational use of pesticides has led to pesticide residues in agricultural products, which is a significant concern. Therefore, establishing rapid and accurate pesticide residue detection methods is crucial for promoting the development of agricultural product quality supervision standards, improving public health and enhancing the ecological environment. Traditional instrumental detection methods have high sensitivity and accuracy, but they cannot meet the needs of real-time rapid detection in the field due to their high professional requirements and difficulty in miniaturization and integration. In contrast, microfluidic chips have developed rapidly owing to their inherent advantages such as miniaturization, low sample consumption and ease of integration. With the growing demand for rapid detection of pesticide residues and continuous innovation in the materials and processes for the preparation of microfluidic chips, the research and development of rapid and highly sensitive detection technology for pesticide residues has become the mainstream direction in this field. This review introduces the materials and manufacturing processes of microfluidic chips used for pesticide residue detection and discusses commonly used fluid driving methods. It also provides a detailed overview of the progress made in applying microfluidic chips for rapid detection of pesticide residues, briefly summarizes existing challenges in the technology, and proposes potential solutions. The goal is to offer insights for the research and development of new methods, new technologies and new products for the rapid detection of pesticide residues. |
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