| 蒋洪1,2;韩亚娟2;张珈敏2;胡远扬2.应用昆虫毒素基因构建重组病毒杀虫剂研究进展[J].植物保护,2007,33(6):1-5. |
| 应用昆虫毒素基因构建重组病毒杀虫剂研究进展 |
| Advances in insect-specific toxin genes for recombinant insect virus |
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| DOI： |
| 中文关键词: 昆虫毒素基因 重组病毒杀虫剂 杆状病毒 生物防治 |
| 英文关键词:insect-specific toxin gene recombinant insect virus baculovirus bio-control |
| 基金项目: |
| 蒋洪1 2;韩亚娟2;张珈敏2;胡远扬2 |
| 1.武汉大学病毒学国家重点实验室 环球生物农药武汉大学联合研发中心 武汉 430072;2.武汉大学基础医学院病原生物学系 武汉 430072 |
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| 中文摘要: |
| 由于基因工程技术的发展和安全性研究的深入,以重组杆状病毒为主的重组昆虫病毒杀虫剂的应用正面临着突破。文章综述了通过插入昆虫专一性毒素基因构建重组昆虫病毒杀虫剂的技术路线,展望重组病毒杀虫剂的发展趋势。 |
| 英文摘要: |
| Biological control of agricultural and urban pests has gained importance in recent years due to increased pressure to reduce the use of chemical insecticides and their residues in the environment and food.Insect viruses are valuable natural control agents and they have been genetically modified to improve their insecticidal activity.There are two major strategies at present,in a broad sense,for improving the timing of killing action of these agents,i.e.interference with host physiology and introduction of an insect-specific toxin.Recombinant insect viruses are efficacious in the laboratory,greenhouse and field trials.Hopefully,the negative influence of social perception of genetically modified organisms on biotechnological research will gradually decrease and recombinant insect viruses will be introduced as an important biological factor in the near future. |
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